15 November 2023

Skin aging: how to reduce the signs of aging with Dionisia products

The skin aging process is influenced by many factors which can be intrinsic, such as sex, genetics and age, or external, such as exposure to sunlight, stress and lifestyle.

However, although less known, the main cause of this natural process is the uncontrolled increase in reactive oxygen species (ROS), i.e. a type of free radical containing oxygen that is normally generated during cellular respiration. In aging, this oxidative stress is associated with both an increase in ROS production and a decrease in our body’s defense mechanisms [1]. The latter makes use of enzyme action produced by our own body and natural antioxidants, introduced through our diet (for example vitamin E) or applied locally through cosmetic products.

To effectively counteract the formation of new ROS and slow down skin aging, a continuous supply of antioxidant molecules is necessary, which by nature have a fairly short life cycle.

How to protect your skin from oxidative stress

Skin aging is also accompanied by a decrease in activity of the skin’s secretory glands, the sebaceous glands, with a consequent reduction in the surface lipid membrane and skin hydration [2]. Furthermore, renewal of the outer layer of skin is increasingly slower: usually the skin then becomes dry, rough, more sensitive and susceptible to inflammatory phenomena [3].

Hence the importance of using cosmetics specially formulated to protect the skin from external pro-oxidative agents and keep it properly hydrated, especially in the areas most exposed to external agents, i.e. hands and face. Numerous experimental tests highlight how antioxidant compounds such as polyphenols, ascorbic acid (vitamin C), tocopherols (vitamin E) and other natural substances reduce oxidative stress and slow down the skin aging process [4]. Polyphenols are among the most studied and we have begun to decipher the molecular mechanisms through which they exert their anti-aging function on dermal cells [5]. Obviously their presence within a cosmetic formulation is not sufficient in itself. The concentrations must be adequate and calibrated to inhibit the pro-oxidative activity of reactive oxygen species and other free radicals.

Dionisia line: proven antioxidant efficacy

In the laboratories of the Istituto Italiano di Tecnologia we experimentally verified the protective and antioxidant effect offered by the extracts of Monterosso al Mare grapes, which proved to be much richer in polyphenols than others similar in nature.

From the result of this research our first anti-aging line Dionisia was born.

In the cosmetic products of the Dionisia Line we have included a quantity of extract equal to or greater than that tested in vitro on cells and included other precious antioxidant compounds to promote a synergistic and more effective function.

Below we will see which ones.

  • Antiage face cream: contains tocopherol (vitamin E), tocopheryl acetate, ascorbyl palmitate (the fat-soluble derivative of ascorbic acid/vitamin C), shea butter (Butyrospermum parkii) and jojoba seed oil ( Simmondsia chinensis).
  • Face serum – Immediate lifting: here we find low molecular weight hyaluronic acid, which penetrates the skin better than those of high molecular weight, guaranteeing even greater effectiveness. This acid in particular was obtained from the algae Macrocystis pyrifera through a biotechnological process. The Macrocystis pyrifera algae is also rich in antioxidant vitamins and the extract obtained from it forms a homogeneous, thin and elastic layer on the skin, with an amazing cosmetic lifting effect.
  • Anti-wrinkle eye contour: tocopherol (vitamin E), tocopheryl acetate, sodium tocopheryl phosphate, ascorbyl palmitate and shea butter are present.

The importance of skin hydrating

In addition to the supply of antioxidants, it is essential to give the skin the right hydration to keep the protective hydrolipidic surface film intact, especially in the areas of the face that are more delicate and subject to the appearance of wrinkles, for example those around the eyes.

Here below you can find a list of the hydrating ingredients contained in the Dionisia Line:

  • Dionisia Antiage face cream contains glucose, sorbitan olivate (a sebum-like emulsifier of natural origin), emollient and protective almond oil (Prunus amygdalus dulcis), shea butter, which is film-forming and nourishing, Illipé (Shorea stenoptera seed butter) with an elasticising and healing effect, very suitable for sensitive skin and Acacia decurrens flower wax, which is deconstructing and regenerating tissues.
  • Sodium hyaluronate is included in the Dionisia Face Serum – Immediate lifting, which is capable of binding considerable quantities of water molecules, giving hydration to the skin.
  • The Dionisia Anti-wrinkle Eye contour contains squalane, capable of regenerating the hydrolipidic film, cetearyl alcohol, cetearyl glucoside, vegetable emulsifiers that limit transepidermal water loss, nourishing and sebum-like avocado oil (Persea gratissima), Acacia decurrens flower wax, shea butter, tocopherol (vitamin E), tocopheryl acetate and sodium tocopheryl phosphate.




[1] F. Papaccio, A. D’arino, S. Caputo, B. Bellei, Focus on the Contribution of Oxidative Stress in Skin Aging, Antioxidants 2022, Vol. 11, Page 1121. 11 (2022) 1121. https: //doi.org/10.3390/ANTIOX11061121.

[2] E. Makrantonaki, C.C. Zouboulis, The skin as a mirror of the aging process in the human organism – State of the art and results of the aging research in the German National Genome Research Network 2 (NGFN-2), Exp. Gerontol. 42 (2007) 879–886. https://doi.org/10.1016/J.EXGER.2007.07.002.

[3] D.J. Tobin, Introduction to skin aging, J. Tissue Viability. 26 (2017) 37–46. https://doi.org/10.1016/J.JTV.2016.03.002.

[4] M. Michalak, Plant-Derived Antioxidants: Significance in Skin Health and the Aging Process, Int. J. Mol. Sci. 2022, Vol. 23, Page 585. 23 (2022) 585. https://doi.org/10.3390/IJMS23020585.

[5] J.H. Lee, J. Park, D.W. Shin, The Molecular Mechanism of Polyphenols with Anti-Aging Activity in Aged Human Dermal Fibroblasts, Mol. 2022, Vol. 27, Page 4351. 27 (2022) 4351. https://doi.org/10.3390/MOLECULES27144351.